Mari Kaymakcian Kayajian

Introduction Ozone therapy has a long history in integrative and alternative medicine, initially developed for its antimicrobial and anti-inflammatory properties. Prolozone therapy is a derivative, coined by Dr. Frank Shallenberger, that merges ozone with proliferative therapy (prolotherapy). Specifically, intraarticular Prolozone injections involve delivering a combination of oxygen/ozone gas and other regenerative substances directly into joint…